Which of the following statements is FALSE about HIV replication?

Question

BlackTom AI · Accepted Answer

We start by listing each statement and assessing its accuracy about HIV replication.
Option a: 'Viral DNA is produced through reverse transcription.' This is true. HIV uses reverse transcriptase to convert its RNA genome into DNA, which is then integrated into the host genome.
Option b: 'The HIV virus matures by protease releasing individual HIV proteins.' This is true. The viral protease cleaves Gag and Gag-Pol polyproteins to produce mature, functional viral proteins during virion maturation.
Option c: 'The fusion of HIV to host cells is blocked by Reverse Transcriptase.' This is false. Fusion of HIV with the host cell membrane is mediated by the envelope glycoprotein gp120/gp41 and requires CD4 and a coreceptor; reverse transcriptase does not block the fusion step. Inhibitors that block fusion act differently (e.g., fusion inhibitors), but RT inhibitors do not prevent fusion directly.
Option d: 'Viral DNA can integrate into host DNA.' This is true. The integrated viral DNA (provirus) is a key step after reverse transcription and nuclear import, facilitated by integrase.
In summary, the only statement that is incorrect is option c, as it misattributes the fusion-blocking role to Reverse Transcriptase rather than recognizing that fusion is a separate entry process and blocked by other mechanisms.

2025-PSB-MIC1IPE(SP-T3-FT) - INFECTIONS, PANDEMICS AND EPIDEMICS

Which of the following statements is FALSE about HIV replication?

查看解析

登录即可查看完整答案

类似问题

A cell infected with rabies virus releases a virion with a genome containing a mutation that prevents the matrix (M) protein from being synthesised correctly. What would you expect to occur if this virion infects another cell? The virus will:[Fill in the blank]

In a host cell infected with the rabies virus, where does viral genome replication occur?

To replicate, a virus or its genetic material must be in a living .

A virus or its genetic material must be in a living host to .

True or False: Viral replication occurs after it attaches and enters the host cell.

4. How do phages reproduce?

Which phrase best summarises the replicative cycle of viruses?

A newly identified virus has a single-stranded RNA genome that is used as mRNA after infection. Its capsid is 25-30 nm in diameter and contains 180 identical capsomeres. Which of the following processes would be the best to follow to analyze the reproduction of this virus in a host cell?

更多留学生实用工具

考试浏览器助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单