How does viral latency challenge disease management in captive populations?

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BlackTom AI · Accepted Answer

Exploring the concept in question, we consider what viral latency means for disease management in captive populations.
Option 1: 'Latency makes viruses easier to eradicate from wildlife populations.' This is misleading because latency enables the virus to hide in hosts without detection, complicating eradication rather than facilitating it. Narrowing the focus to elimination is unrealistic when latent reservoirs can persist for long periods.
Option 2: 'Latent infections are always symptomatic, making infected animals easy to identify.' In reality, latency is typically characterized by a lack of symptoms; animals can appear healthy while harboring dormant virus, which undermines detection and control efforts.
Option 3: 'Latent herpesviruses cannot be transmitted to other animals.' This statement ignores the possibility of reactivation leading to shedding and potential transmission during periods of latency, or through latent carriers that intermittently become infectious, so it is not accurate.
Option 4: 'Latency allows the virus to persist undetected, potentially reactivating under stress.' This captures the core challenge: latent infections can evade routine monitoring, remain hidden in reservoirs, and reactivate when stressors compromise immunity, leading to new waves of disease despite apparent health.
In summary, the key difficulty for management arises from the hidden persistence of latency and the risk of reactivation, which complicates surveillance, quarantine, and treatment strategies. The other options misrepresent latency by assuming easy detection, constant symptoms, or impossibility of transmission, all of which would undermine a realistic understanding of disease dynamics in captive populations.

ANSC20003_2025_SM2 ANSC20003 - Topics in Animal Health (ANSC20003) - Mid-semester Exam

How does viral latency challenge disease management in captive populations?

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