题目
BIOL 251 Clinical Connections 9: The Grave Diagnosis
多重下拉选择题
Fill in the chart to determine whether the etiology would lead to hypothyroidism or hyperthyroidism and whether it will increase or decrease T3/T4 and TSH levels. (the first one has been done for you) Etiology Hypo or Hyperthyroidism Level of T3/T4 Level of TSH Pituitary tumor that destroys TSH-producing cells Hypothyroidism Decrease Decrease Proliferating pituitary tumor [ Select ] Hyperthyroidism Hypothyroidism [ Select ] Increase Decrease [ Select ] Increase Decrease Thyroid tumor that destroys cells [ Select ] Hypothyroidism Hyperthyroidism [ Select ] Increase Decrease [ Select ] Increase Decrease Proliferative thyroid tumor [ Select ] Hypothyroidism Hyperthyroidism [ Select ] Decrease Increase [ Select ] Increase Decrease
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标准答案
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思路分析
Carefully restating the setup helps align our thinking with the biology involved.
- The first row: Pituitary tumor that destroys TSH-producing cells → this reduces TSH output, which lowers thyroid hormone production. Therefore: Hypothyroidism, with Decreased T3/T4 and Decreased TSH due to suppressed or reduced TSH signal being removed.
- The second row: Proliferating pituitary tumor → if it secretes excess TSH, this would drive thyroid hormone production up. Therefore: Hyperthyroidism, with Increased T3/T4 and Increased TSH via the pituitary overproduction signal.
- The third row: Thyroid tumor that destroys cells → destruction of thyroid follicular cells lowers T3/T4 output; the pituitary respon......Login to view full explanation登录即可查看完整答案
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