Anfinsen experiment demonstrated that protein......... is encoded in a protein's ...............................structure and was dependent on the ................................of Ribonuclease A

Question

BlackTom AI · Accepted Answer

Clarifying the prompt, we’re asked to evaluate which statement about the Anfinsen experiment is correct and why.
Option 1: 'structure/secondary/folding' claims that the protein's structure is encoded in its secondary structure and that folding relates to secondary structure. This is not aligned with Anfinsen’s key insight, which emphasizes the primary sequence (not secondary) as the encoding source for the native fold. Therefore this option misplaces where information about folding is stored.
Option 2: 'folding/secondary/performance' suggests that folding is encoded in secondary structure and that performance (function) follows from that. Since the concept is about primary sequence encoding the folding, and secondary structure is not the primary repository of that information, this choice mixes up the correct level and uses an odd term ('performance') where activity is more standard. This makes it incorrect.
Option 3: 'folding/primary/activity' states that folding is encoded in the primary structure and that the activity depends on proper folding. This matches the essence of Anfinsen’s experiments: the information for the native, functional conformation resides in the amino acid sequence (primary structure), and correct folding is required for enzymatic activity.
Option 4: 'structure/tertiary/activity' asserts that the structure (specifically tertiary) encodes the native state and that activity follows from it. While the native state often corresponds to a specific tertiary arrangement, Anfinsen’s key claim is that this information is contained in the primary sequence, not that tertiary structure encodes folding. This makes the statement inaccurate as a description of the fundamental finding.
In summary, the correct interpretation aligns with the idea that folding is dictated by the primary sequence and that proper folding enables enzymatic activity, while the other options misstate where the encoding resides or what is being linked to activity.

BIOL3611.13541.202610 ClassMeeting7

Anfinsen experiment demonstrated that protein......... is encoded in a protein's ...............................structure and was dependent on the ................................of Ribonuclease A

查看解析

登录即可查看完整答案

类似问题

Gene expression is considered “complete” when:

Fill in the boxes and the titles of the figure shown above

The role of betamercaptoethanol and urea in Anfinsen's experiment is respectively

Why is the hydrophobic effect essential in protein folding?

If a protein is slightly misfolded, it could be because of

If a protein is slightly misfolded, it could be because of

更多留学生实用工具

考试浏览器助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单