Question at position 67 Which of the following is NOT a human PRION disease?Chronic Traumatic EncephalopathyKuruFatal Familial InsomniaCreutzfeldt-Jakob DiseaseClear my selection

Question

BlackTom AI · Accepted Answer

When evaluating which option is NOT a human prion disease, we need to recall the hallmark features of prion diseases and how each condition presents.
Option 1: Chronic Traumatic Encephalopathy. This condition results from repeated head injuries and is characterized by tau protein pathology (tau tangles) rather than misfolded prion proteins. It is not categorized as a prion disease and is linked to trauma history, not prion transmission. Thus, it stands as the non-prion option among the choices.
Option 2: Kuru. This is a classic human prion disease transmitted through ritual cannibalism in certain populations. It involves misfolded prion proteins and causes rapidly progressive neurodegeneration. Therefore, it is indeed a prion disease, not a non-prion disease.
Option 3: Fatal Familial Insomnia. FFI is caused by a mutation in the PRNP gene, leading to abnormal prion protein formation and a hereditary prion disease. Its inheritance pattern and pathophysiology are quintessential prion disease features, so it is not the correct non-prion choice.
Option 4: Creutzfeldt-Jakob Disease. CJD is the prototypical human prion disease, occurring in sporadic, familial, or iatrogenic forms, with rapid dementia and spongiform changes. This is clearly a prion disease, not the non-prion option.
In summary, understanding the etiologies shows that prion diseases involve misfolded prion proteins and often transmissible or genetic mechanisms, whereas Chronic Traumatic Encephalopathy is driven by repetitive trauma and tauopathy, not prions.

Question at position 67 Which of the following is NOT a human PRION disease?Chronic Traumatic EncephalopathyKuruFatal Familial InsomniaCreutzfeldt-Jakob DiseaseClear my selection

查看解析

登录即可查看完整答案

类似问题

Question at position 60 Why is it so difficult to develop treatments for prion diseases?The causative agent is a self-proteinIt is not a bacteriaMutations make vaccine development difficultAll of the aboveClear my selection

Question at position 59 Which of the following is NOT a Transmissible Spongiform Encephalopathy (TSE)?KuruChronic Wasting DiseaseScrapieall are TSEsClear my selection

Question at position 49 The Kuru outbreak in Papua New Guinea was halted by:the imposition of a ban on a historical cultural practicethe eradication of a bat vectorproper sanitationthe development of a vaccineClear my selection

Question at position 31 Bovine spongiform encephalopathy is also known as:mad cow diseaseKurumad dog diseasecrazy cow diseaseClear my selection

What is a characteristic feature of the brain tissue in patients with Transmissible Spongiform Encephalopathies (TSEs)?

In a consumer society, many adults channel creativity into buying things

Economic stress and unpredictable times have resulted in a booming industry for self-help products

People born without creativity never can develop it

更多留学生实用工具

考试浏览器助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单