Which of the following is NOT a feature of osteoarthritis?
下列哪项不是骨关节炎的特征？

Question

BlackTom AI · Accepted Answer

Question focus: identifying which item is not a feature of osteoarthritis (OA).
Option 1: Joint deformities 关节畸形. In OA, especially advanced cases, joint deformities can develop due to uneven wear and cartilage loss, so this can be a feature. Therefore this option is not the correct choice for 'not a feature'.
Option 2: Decreased range of motion 活动范围减小. OA commonly leads to reduced range of motion because cartilage loss, osteophyte formation, and joint stiffness limit movement. This is a true feature of OA.
Option 3: Auto-antibodies. OA is primarily non-inflammatory and not driven by autoantibody-mediated immune responses; auto-antibodies are characteristic of some inflammatory arthritides (like rheumatoid arthritis), not OA. This makes this option a strong candidate for 'NOT a feature'.
Option 4: Stiffness with inactivity 僵硬伴不活动. Stiffness after periods of inactivity is a classic symptom of OA, often referred to as morning stiffness lasting under 30 minutes. This aligns with OA features.
Option 5: Crepitus. Crepitus, or a grinding/grating sensation with joint movement, is commonly described in OA due to roughened articular surfaces and loose osteophytes. This is indeed a feature.
In summary, most options describe typical OA features (deformities, decreased ROM, stiffness with inactivity, crepitus), while auto-antibodies are not a characteristic mechanism or finding in OA. Therefore, Auto-antibodies stands out as not being a feature of osteoarthritis. The reasoning aligns with OA being largely degenerative and non-autoimmune in its pathophysiology.

BIOL 251 杂志251年 Clinical Connections 4: A Joint Effort 临床联系4：共同努力

Which of the following is NOT a feature of osteoarthritis? 下列哪项不是骨关节炎的特征？

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