2. The rapid delivery of nicotine from smoking cigarettes contributes to its reinforcing properties. However, the slow delivery of nicotine from OTC nicotine replacement therapy contributes to its therapeutic efficacy.

Question

2. The rapid delivery of nicotine from smoking cigarettes contributes to its reinforcing properties.  However, the slow delivery of nicotine from OTC nicotine replacement therapy contributes to its therapeutic efficacy.

BlackTom AI · Accepted Answer

The statement presents two linked ideas about nicotine delivery and its effects in different contexts.

Option 1: rapid delivery contributes to reinforcing properties. This is accurate because cigarettes deliver nicotine quickly to the brain, causing an abrupt dopamine surge that strengthens the association between smoking cues and the pleasurable effects. The rapid pharmacokinetic profile is central to the high reinforcing potential of smoking.

Option 2: slow delivery from OTC nicotine replacement therapy contributes to therapeutic efficacy. This is also correct. OTC NRTs are designed to provide a steadier, lower nicotine exposure to prevent withdrawal symptoms without producing the rapid spikes that drive reinforcement and craving. The slower delivery helps normalize nicotine levels over time and supports long-term cessation or reduced dependence.

Potential misconceptions to avoid:
- If someone assumes that slow delivery cannot be effective therapeutically, that would ignore the purpose of NRT: to reduce withdrawal and cravings by maintaining a controlled nicotine level.
- If one believes only rapid delivery has any therapeutic value, it overlooks how sustained nicotine exposure, even at lower rates, can aid withdrawal management and relapse prevention.

In summary, both statements correctly reflect the distinct roles of nicotine delivery speed: rapid delivery underpins reinforcement in smoking, while slow delivery underpins the therapeutic efficacy of NRT.

PHR 2410 SP2025 (36478) MODULE 5 | Quiz #10

2. The rapid delivery of nicotine from smoking cigarettes contributes to its reinforcing properties. However, the slow delivery of nicotine from OTC nicotine replacement therapy contributes to its therapeutic efficacy.

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