Which of the following is TRUE?

Sister chromatids:

Question

Which of the following is TRUE?

Sister chromatids:

BlackTom AI · Accepted Answer

To tackle the question, let's compare what each option says about Sister chromatids across the stages of mitosis.
Option 1: 'arise by replication during prophase.' This is misleading. Sister chromatids are the two identical copies produced when DNA is replicated during S phase, not formed anew during prophase. Prophase involves condensation and spindle formation, not the creation of sister chromatids. So this statement is inaccurate.
Option 2: 'segregate from each other during each mitotic anaphase.' During anaphase, the sister chromatids are pulled apart toward opposite poles as the cohesin proteins holding them together are cleaved. This aligns with the standard description of chromatid separation and is therefore true.
Option 3: 'can contain two versions with different genetic information.' By definition, sister chromatids are identical copies of a chromosome, barring rare mutations, so they do not contain different genetic information. That statement contradicts the fundamental concept of sister chromatids and is incorrect.
Option 4: 'segregate from each other during each mitotic metaphase.' Metaphase is when homologous chromosomes line up at the metaphase plate, and sister chromatids are still held together; they do not segregate during metaphase. Separation occurs during anaphase, not metaphase, making this option false.
In summary, the only option that accurately describes the behavior of sister chromatids is the one stating they segregate from each other during anaphase. The remaining options either misplace the timing (metaphase) or describe processes that do not apply to sister chromatids (arising during prophase, carrying different genetic information).

BIOL 1009 (001-006/050-055) Midterm Exam III

Which of the following is TRUE? Sister chromatids:

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