The phase of mitosis in which the centromeres split and sister chromatids are pulled to opposite poles of the cell is

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The question asks: The phase of mitosis in which the centromeres split and sister chromatids are pulled to opposite poles of the cell is

Since the answer_options field is empty, there are no listed alternatives to evaluate individually. We can still reason through the concept based on standard mitosis stages.

Key concept: during mitosis, sister chromatids are held together at the centromere until anaphase. When anaphase begins, the separase enzyme cleaves the cohesin proteins that hold sister chromatids together, causing the centromeres to split. Once split, motor proteins and microtubules shorten and pull the now-separated chromatids (which are considered individual chromosomes) toward opposite poles of the cell. This movement ensures that each daughter cell will receive an identical set of chromosomes.

Why this phase fits the description: the defining event—centromere split followed by movement to opposite poles—occurs specifically in anaphase. In prophase, chromosomes condense but centromeres do not split; in metaphase, chromosomes align at the center without centromere separation; in telophase, chromosomes arrive at the poles and begin decondensing, with reformation of the nuclear envelope. Thus, the described process corresponds to the anaphase stage.

If options were present, the incorrect choices would likely reference prophase, metaphase, or telophase, each having distinct hallmark events: prophase involves chromatin condensing and spindle formation; metaphase features chromosome alignment at the equatorial plate; telophase involves reformation of the nuclear envelope and chromosome de-condensation. Understanding these distinct events helps prevent mislabeling the phase based on partial observations.

In summary, the described event—centromere separation and chromatids pulled to opposite poles—is the hallmark of anaphase in mitosis, due to the separation of sister chromatid cohesion and active movement toward opposite ends of the cell.

Biol-100-OLH-OMH-ONH Quiz #8

The phase of mitosis in which the centromeres split and sister chromatids are pulled to opposite poles of the cell is

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