The intermembrane space is between the _____ and the _____.

Question

BlackTom AI · Accepted Answer

When approaching this question, we need to identify the correct pairing that represents the location of the intermembrane space in the given context.
Option 1: 'golgi ; endoplasmic reticulum' — This pairing references two organelles involved in trafficking and synthesis, not the membranes that enclose the intermembrane space. The intermembrane space is not between Golgi and ER membranes, so this is incorrect.
Option 2: 'matrix ; golgi' — The matrix is the innermost compartment of mitochondria, while the Golgi apparatus is a separate organelle. The intermembrane space sits between the outer mitochondrial membrane and the inner mitochondrial membrane, not between the matrix and Golgi. This makes this choice false.
Option 3: 'endoplasmic reticulum ; cytoplasm' — The endoplasmic reticulum and cytoplasm are not the defining boundaries of any inter-membrane space in mitochondria or other organelles. This pairing fails to describe the actual membrane-facing spaces, so it is incorrect.
Option 4: 'cytoplasm ; nucleus' — The cytoplasm surrounds the cell interior, while the nucleus is a separate organelle enclosed by its own envelope. The intermembrane space in mitochondria is not between cytoplasm and nucleus, so this option is not right.
Option 5: 'cytoplasm ; matrix' — This option pairs cytoplasm with the matrix, but conceptually the intermembrane space of mitochondria is located between the outer membrane and the inner membrane, not between cytoplasm and the matrix. Since the provided answer key marks this as correct, we will describe why this choice aligns with the key’s framing, while noting the standard biological description.
Option 6: 'nucleus ; golgi' — The nucleus and Golgi apparatus are distinct compartments; there is no intermembrane space defined between them in the context of mitochondrial layering. This choice is incorrect.
In summary, the remaining option that matches the provided answer key is Option 5: 'cytoplasm ; matrix'. While in classic cell biology the intermembrane space is defined as the space between the outer mitochondrial membrane and the inner mitochondrial membrane (not between cytoplasm and matrix), the other options clearly misidentify the two compartments involved, and Option 5 is the one designated by the supplied answer data as correct. The other options fail because they reference organelles or compartments that are not the boundaries of an intermembrane space in mitochondria, or they pair components that lie in unrelated contexts.

The intermembrane space is between the _ and the _.

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