Above is an image of a polypeptide located within the cell membrane. Its function is to pick up signals from either side of the membrane and convey them to the other side.

Which of the following statements about this polypeptide is likely to be true?

Question

Above is an image of a polypeptide located within the cell membrane. Its function is to pick up signals from either side of the membrane and convey them to the other side.

Which of the following statements about this polypeptide is likely to be true?

BlackTom AI · Accepted Answer

Examining the question, we’re told the polypeptide is located within the cell membrane and functions to relay signals across it. The image shows a membrane with distinct hydrophobic regions spanning the lipid bilayer, consistent with a transmembrane protein that has segments crossing the bilayer to transmit signals.
Option 1: There are 3 areas of this polypeptide that are mostly hydrophobic. In membrane proteins, hydrophobic (nonpolar) stretches typically form the transmembrane helices that cross the lipid bilayer. The image appears to depict several such hydrophobic segments crossing the membrane, suggesting multiple transmembrane domains. If three such stretches meet the profile of a transmembrane protein, this option aligns with the general architecture seen in many signal-transducing proteins.
Option 2: There are 4 areas of this polypeptide that are mostly hydrophobic. While it’s possible for some transmembrane proteins to have four hydrophobic spans, the visual evidence in the picture emphasizes a smaller number of crossing regions. If the depicted protein shows three prominent hydrophobic segments, claiming four would overcount relative to what’s illustrated. Miscounting transmembrane spans is a common source of error when interpreting such diagrams.
Option 3: The areas marked with ✱ are hydrophobic. The diagram includes star marks on certain portions of the polypeptide. If the stars are intended to denote hydrophobic stretches, this option could be correct. However, without explicit legend stating what the ✱ marks correspond to, relying on the symbol alone risks misinterpretation. The correctness depends on how the diagram’s legend defines those marks.
Option 4: The hydrophilic parts of the membrane allow this protein to be embedded within it. Hydrophilic (polar) regions interact with aqueous environments and are not the parts that traverse the lipid core. Transmembrane proteins typically have hydrophobic regions that span the hydrophobic core of the membrane, while hydrophilic regions tend to be on the surfaces, near the aqueous exterior or interior. Therefore, describing embedding based on hydrophilic membrane portions contradicts the standard model of transmembrane protein architecture.

Above is an image of a polypeptide located within the cell membrane. Its function is to pick up signals from either side of the membrane and convey them to the other side. Which of the following statements about this polypeptide is likely to be true?

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