A patient should be fasted prior to collecting a serum sample for analysis in order to prevent what happening to the serum?

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BlackTom AI · Accepted Answer

To begin, the question asks about the reason for fasting before drawing a serum sample for analysis. The key concept is that recent dietary fat intake leads to the presence of lipids in the bloodstream.
In particular, after meals, triglyceride-rich lipoproteins such as chylomicrons are produced and circulate, causing the serum to appear lipemic (milky) and potentially altering certain laboratory measurements. Therefore, fasting helps reduce this lipemic interference.
If the patient has eaten recently, the serum may become lipemic, which can interfere with spectrophotometric assays, affect concentration readings, and compromise the accuracy of tests that rely on clear serum, such as cholesterol, enzyme, or hormone assays. Fasting minimizes these lipemic effects and yields a more reliable baseline for measurement.
Because there were no answer options provided in the data, there is nothing to evaluate as correct or incorrect among choices. However, the core concept remains that fasting prior to serum collection is intended to prevent lipemia in the serum by avoiding recent dietary fat absorption.
In summary, the purpose of fasting is to prevent lipemic serum caused by postprandial lipids, ensuring more accurate and interpretable laboratory results.

VT122 (Assignment) Post Lab Activity: Hematology I & II - DUE 2/3 BY MIDNIGHT

A patient should be fasted prior to collecting a serum sample for analysis in order to prevent what happening to the serum?

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What is the term for an opaque and milky look to serum or plasma that is most a result of high level of lipids (or fats) in blood, which can be avoid by fasting the patient prior to blood collection?

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