Ligand gated ion channels can be found:

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BlackTom AI · Accepted Answer

Exploring the question about where ligand-gated ion channels can be found requires evaluating each option in light of what ligand-gated channels do.
Option 1: 'In vesicles' — While receptors and channels may be packaged in vesicles within cells, ligand-gated ion channels themselves function as membrane proteins located in the cell membrane. This option confuses intracellular storage with functional location, so it is not the most accurate description of typical ligand-gated ion channel localization.
Option 2: 'At the motor end plate' — This is consistent with classic neurophysiology. The nicotinic acetylcholine receptor at the neuromuscular junction is a quintessential ligand-gated ion channel that opens in response to acetylcholine binding, allowing ion flow and depolarization of the muscle membrane. Therefore, this option correctly identifies a common site of ligand-gated ion channels.
Option 3: 'Associating with oligodendrocytes' — Oligodendrocytes are glial cells involved in myelination in the CNS. While they support neurons, ligand-gated ion channels are not characteristically described as associating with oligodendrocytes as a primary functional location. This makes the option misleading or incorrect for the typical localization of these channels.
Option 4: 'In Type B cells' — Type B cells are not a standard anatomical or physiological context commonly associated with ligand-gated ion channels. Without a clear, established connection to ligand-gated receptor function in these cells, this choice is not supported by typical textbook associations.
In summary, the statement that best aligns with established biology is the one placing ligand-gated ion channels at the motor end plate, where acetylcholine-activated channels mediate rapid synaptic transmission at the neuromuscular junction.

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Ligand gated ion channels can be found:

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