What is the pI of the given amino acid?

Question

BlackTom AI · Accepted Answer

The question as provided is: 'What is the pI of the given amino acid?' with no answer options given. Since there is no specific amino acid structure described or displayed, we cannot compute or confirm a numerical pI.

Key concept: the isoelectric point (pI) of an amino acid depends on its pKa values, which in turn depend on the particular side chain (R group) and whether you are considering the free amino acid or a peptide. For simple amino acids:
- acidic amino acids have pI around 2–3.
- basic amino acids have pI around 9–11 (e.g., lysine ~9.74, arginine ~10.76).
- histidine has a pI around 7.6.

Because the image or data showing the specific amino acid is missing from the prompt, the stated answer of 10.4 cannot be verified. If the amino acid were arginine, a typical pI is near 10.7, not exactly 10.4. If the amino acid were lysine, the pI would be closer to 9.7. For histidine, the pI would be near 7.6. Therefore, without the exact identity or structural information, the numerical value 10.4 cannot be confirmed as correct.

If you have the amino acid structure or name, you can determine the pI by:
- listing the pKa values of the charged groups (N-terminus, C-terminus, and side chain as applicable),
- identifying the pH at which the net charge is zero (i.e., where the amino acid is electrically neutral),
- or using a standard table of pI values for common amino acids.

In summary, with the given prompt lacking the specific amino acid, we cannot validate the 10.4 pI value. Providing the amino acid identity or its structural drawing would allow a precise calculation or lookup.

What is the pI of the given amino acid?

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The titration curve for glycine is shown below. The key points are designated I to V. Select the the point on the titration curve where the average net charge of glycine is zero

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