True or false: Research indicates that moderate weight loss (i.e., 5% of initial body weight) can improve insulin sensitivity and thereby improve blood glucose control.

Question

BlackTom AI · Accepted Answer

Topic framing: The statement asks about whether research shows that modest weight loss, around 5% of initial body weight, can enhance insulin sensitivity and lead to better blood glucose control. 
Option 1: True. Across numerous studies, even modest weight reductions (about 5–7% of body weight) are associated with meaningful metabolic improvements. Mechanistically, shedding fat mass, particularly visceral fat, tends to reduce inflammatory mediators and free fatty acids, which can improve insulin signaling in tissues like muscle and liver. Clinically, this translates to improved insulin sensitivity and better glycemic metrics such as lower fasting glucose and improved HbA1c in people with insulin resistance, prediabetes, or type 2 diabetes. Thus, the assertion aligns with the bulk of evidence that weight loss can meaningfully impact glucose metabolism when the loss is of a clinically relevant magnitude. 
Option 2: False. Arguing against this would require claiming that moderate weight loss has no impact on insulin sensitivity or glucose control. In that case, one would be ignoring a substantial body of randomized and observational data showing positive metabolic responses to weight reduction. While the degree of improvement can vary among individuals due to genetics, baseline metabolic state, and adherence to lifestyle changes, the general trend supports improvement, not a complete lack of effect. 
Option 3: Both none and some studies suggest no effect. This would be inconsistent with the overall consensus, as the majority of well-conducted research indicates at least some improvement in insulin sensitivity with modest weight loss. It’s important to acknowledge variability, but that does not equate to a universal null effect. 
Option 4: It only affects insulin levels, not sensitivity or glucose control. This is inaccurate because insulin sensitivity is a central determinant of how effectively insulin lowers blood glucose; weight loss tends to improve sensitivity, which in turn improves glucose control. Focusing solely on insulin levels without addressing sensitivity misses the core mechanism by which weight loss exerts metabolic benefits. 
In summary, the strongest and most consistent interpretation of the literature is that moderate, around-5% weight loss can improve insulin sensitivity and, as a consequence, blood glucose control, though individual results may vary based on several factors.

HUMNTR 2410 SP2025 (15848) 营养实验室：糖尿病

True or false: Research indicates that moderate weight loss (i.e., 5% of initial body weight) can improve insulin sensitivity and thereby improve blood glucose control.

查看解析

登录即可查看完整答案

类似问题

Insulin is more effective in the presence of which mineral?

How do GH and IGF-1 differ in their influence on insulin sensitivity?

In a consumer society, many adults channel creativity into buying things

Economic stress and unpredictable times have resulted in a booming industry for self-help products

People born without creativity never can develop it

A product has a selling price of $20, a contribution margin ratio of 40% and fixed cost of $120,000. To make a profit of $30,000. The number of units that must be sold is: Type the number without $ and a comma. Eg: 20000

Which of the following statement regarding cost is correct:

Under the assumptions used in cost-volume-profit analysis, as the activity increases:

更多留学生实用工具

考试浏览器助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单