An increase in the plasma amino acid concentration
Blank
______ insulin secretion.

Question

An increase in the plasma amino acid concentration 
Blank
______ insulin secretion.

BlackTom AI · Accepted Answer

When amino acids rise in the bloodstream, pancreatic beta cells sense these nutrients and respond by secreting insulin. 
Amino acids such as arginine and leucine can directly depolarize beta cells or enhance ATP production, leading to calcium influx and exocytosis of insulin-containing granules. This mechanism helps promote amino acid uptake and utilization by tissues and maintains protein synthesis.
In contrast, the option that amino acids inhibit insulin secretion is incorrect because amino acids do not suppress beta-cell activity; rather, they act as a stimulus under many physiological conditions.
Similarly, stating that amino acid elevation has no effect on insulin secretion is inaccurate since there is a well-established, direct stimulatory relationship between elevated plasma amino acids and insulin release, particularly with certain amino acids that robustly provoke secretion.
Thus, among the choices, the true statement is that an increase in plasma amino acid concentration stimulates insulin secretion.

An increase in the plasma amino acid concentration Blank ______ insulin secretion.

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