The fragment of preproinsulin called c-peptide:

Question

BlackTom AI · Accepted Answer

The provided item appears to be missing its answer options, which makes it impossible to compare multiple statements as required by a typical multiple-choice analysis.

What we do know from the prompt is the statement presented as an answer: "The fragment of preproinsulin called c-peptide: is not essential, people can live decades without it."

Context you should know about c-peptide: during insulin synthesis, preproinsulin is processed to proinsulin and then to insulin plus C-peptide, which are released in equimolar amounts. The C-peptide itself is not an insulin molecule and, for many years, was considered biologically inactive. Modern research has explored potential physiological roles for C-peptide (such as potential effects on microvascular blood flow or nerve function), but its essentiality for life and basic glucose regulation is not established. In clinical practice, individuals without endogenous insulin production (e.g., type 1 diabetes) would lack C-peptide, yet can live with appropriate insulin therapy; thus, C-peptide is not considered essential for survival.

Because there are no other answer choices to evaluate here, we can’t assess which statements would be correct or incorrect in comparison. If the original task intended multiple options, the evaluation would typically include:
- Option A: evaluating whether C-peptide is essential for survival and whether life without it is compatible with good health, citing that insulin is the critical hormone and C-peptide’s role is not essential for life.
- Option B: assessing any claims about metabolic or physiological necessity tied to C-peptide, clarifying the distinction between a biomarker of secretion and a required bioactive component for glucose homeostasis.
- Option C: addressing any erroneous statements that might claim C-peptide directly regulates insulin or glucose without signaling pathways, or that its absence would prevent adaptation.

In summary, the single statement provided aligns with the general understanding that C-peptide is not essential for life, but due to the absence of other options, a complete option-by-option analysis cannot be performed here.

BME 3 Treating Diabete... Week 9 Innovations in insulin delivery

The fragment of preproinsulin called c-peptide:

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