题目
Organic Chemistry Labs - CHEM2003 (UNUK) (24-25) 1 - Grignard PreLab
匹配题
How many equivalents of Grignard reagent are required? 1: How many equivalents of the Grignard reagent will an ester react with? ____ 2: How many equivalents of the Grignard reagent will a ketone react with? ____ 3: How many equivalents of the Grignard reagent will a nitrile react with? ____
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标准答案
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思路分析
We’re asked to determine how many equivalents of Grignard reagent are required for three different carbonyl compounds. Below is a breakdown of each subquestion and reasoning for the given numbers.
1) Ester: How many equivalents of the Grignard reagent will an ester react with? ____
- Esters react with Grignard reagents through a two-step sequence. First, one equivalent of RMgX adds to the carbonyl carbon, forming a tetrahedral intermediate and collapsing to give a ketone with the leaving group (alkoxide) expelled. However, keton......Login to view full explanation登录即可查看完整答案
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