Which of the following best describes the net organic products formed during the oxidation of one molecule of glucose to two molecules of pyruvate via glycolysis

Question

BlackTom AI · Accepted Answer

First, recall the glycolysis outcome when one glucose molecule is converted into two pyruvate molecules. Net ATP and NADH production must reflect both the energy investment and payoff steps.

Option 1: '1 ATP + 1 NADH' — This undercounts both ATP and NADH. In glycolysis, two ATP are net gained (after spending two in the early steps), and two NADH are produced later in the pathway. Therefore, this option misses one ATP and one NADH, making it incorrect.

Option 2: '2ATP+0NADH' — Here, the ATP part is correct in net terms, but it omits the NADH produced. Since glycolysis also yields two NADH molecules per glucose, this option fails to account for NADH production, rendering it false.

Option 3: '2ADP+2NAD+' — This describes substrates rather than products of glycolysis. ADP and NAD+ are consumed earlier, but the net products are ATP and NADH, not ADP or NAD+. Additionally, glycolysis yields phosphorylated energy carriers, not free ADP or NAD+. Thus, this option is incorrect.

Option 4: '2ATP+2NADH' — This matches the classic net products of glycolysis: two ATP molecules net gained and two NADH molecules produced per glucose as it is split into two pyruvate molecules. The overall stoichiometry aligns with the recognition that four ATP are generated in substrate-level phosphorylation, offset by two ATP consumed early, and two NADH are formed during glyceraldehyde-3-phosphate dehydrogenase step. This option accurately reflects the net organic products of glycolysis.

Which of the following best describes the net organic products formed during the oxidation of one molecule of glucose to two molecules of pyruvate via glycolysis

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