One of the mRNA codons for the amino acid Threonine is ACG (reading 5'-3'), what is the corresponding tRNA anticodon for this amino acid (reading 3'-5')?

Question

BlackTom AI · Accepted Answer

To find the tRNA anticodon that pairs with the mRNA codon, first note the codon is 5'-ACG-3' for threonine. The antiparallel, complementary anticodon must run 3'-UGC-5' to pair correctly with ACG in standard base pairing (A-U and C-G, with orientation opposite between codon and anticodon).

Option a: CGU. This sequence would pair with a codon 5'-ACG-3' only if read in the same orientation as a traditional anticodon, which is not the case here; it does not form proper Watson-Centon base pairs with ACG in the required antiparallel arrangement.

Option b: UGA. This is a stop codon, not an anticodon for threonine, so it cannot pair with ACG to insert threonine.

Option c: UGC. This matches the correct antiparallel complement (3'-UGC-5' pairing to 5'-ACG-3'), delivering threonine during translation.

Option d: ACG. This is the same sequence as the codon, but anticodons must be read 3'-5' to pair antiparallel to a 5'-3' codon; using ACG would not create the correct antiparallel arrangement and would not pair properly.

In summary, only UGC (option c) provides the correct antiparallel complement to 5'-ACG-3' for threonine in standard base-pairing rules.

BPS3021 S1 2025 Week 5 | CYL quiz

One of the mRNA codons for the amino acid Threonine is ACG (reading 5'-3'), what is the corresponding tRNA anticodon for this amino acid (reading 3'-5')?

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