If angular cheilitis is treated with a fluconazole and terconazole ointment or cream and the condition clears up, it was MOST likely caused by

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Reiterating the question: If angular cheilitis is treated with a fluconazole and terconazole ointment or cream and the condition clears up, it was MOST likely caused by

Option 1: A fungal infection. Fluconazole and terconazole are antifungal medications. A positive response to these drugs strongly suggests a fungal etiology, such as Candida species, which aligns with typical angular cheilitis presentations that improve with antifungal therapy.

Option 2: A bacterial infection. While angular cheilitis can be complicated by bacterial colonization (for example with Staphylococcus aureus), antibiotics targeting bacteria would be expected to improve bacterial-driven lesions. Since the treatment here is antifungal and the lesion resolves, this option is less likely.

Option 3: A nutritional deficiency. Nutritional problems (e.g., iron or B vitamins) can predispose to angular cheilitis, but they are not typically resolved solely by antifungal creams. If a nutritional deficiency were the primary cause, antifungal therapy would not produce a sustained cure without correcting the underlying deficiency.

Option 4: Cold weather. Cold or dry weather can worsen or predispose to angular cheilitis by drying the lips, but this factor does not produce a lesion that would respond specifically to antifungal medications. The resolution with antifungals points away from a weather-only cause.

Option 5: A denture. Denture-associated angular cheilitis can occur due to mechanical irritation or hygiene issues, and it may sometimes require antifungal treatment if a fungal component is present. However, the prompt specifies that antifungal therapy alone led to clearing, making a primary fungal infection the more direct explanation rather than denture use alone.

In summary, the effectiveness of antifungal therapy directly supports a fungal etiology, while the other options describe causes or contributors that would not typically be cured solely by antifungal agents.

OC_DHYG402_202501SPI_1 National Board Practice Exam #1

If angular cheilitis is treated with a fluconazole and terconazole ointment or cream and the condition clears up, it was MOST likely caused by

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