Think about the medication Eli is taking. What is the mechanism of action (or drug action) of the active ingredient that will address Eli's cough symptoms?

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BlackTom AI · Accepted Answer

To determine the mechanism of action for Eli's cough medication, we must match the active ingredient to its drug action and the symptom it targets.
Option 1: 'Acts in the brainstem to increase the cough threshold' describes an antitussive effect. Medications like dextromethorphan or codeine suppress cough by acting on the central nervous system, specifically the cough center in the brainstem, raising the threshold for coughing. This would reduce coughing rather than address mucus directly.
Option 2: 'Reduces volume of nasal mucous by constricting relevant blood vessels' refers to decongestants. These agents, such as pseudoephedrine or phenylephrine, cause vasoconstriction in nasal mucosa to lessen nasal secretions. They do not primarily affect mucus in the lungs and thus are not the best match for a cough stemming from pulmonary mucus.
Option 3: 'Loosens and thins mucous within the lungs' corresponds to expectorants like guaifenesin. By decreasing mucus viscosity, these agents facilitate coughing up phlegm from the airways, directly addressing the lung mucus that can provoke coughing.
Option 4: 'Reduces the inflammatory response by blocking histamine receptors' describes antihistamines. While histamine blockade can help with allergic symptoms, they do not primarily reduce mucus viscosity in the lungs nor target cough via mucus clearance.
In summary, for a cough driven by thick or abundant mucus in the lungs, a mechanism that loosens and thins pulmonary mucus (expectorant action) provides the most direct relief, whereas the other options describe central suppression of cough, nasal decongestion, or anti-inflammatory effects that don’t specifically enhance clearing of lung mucus.

PHR 2410 SP2025 (36478) MODULE 3 | Case Study #2 - Part I

Think about the medication Eli is taking. What is the mechanism of action (or drug action) of the active ingredient that will address Eli's cough symptoms?

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