题目
题目

CHE 008B A01 SS1 2025 Lecture 3 - Epoxides

多重下拉选择题

Epoxides react with nucleophiles on the more substituted side in acidic conditions. This will invert the stereochemistry at the reacting carbon and will not invert the stereochemistry at the non-reacting carbon. This is a SN2 mechanism.

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标准答案
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思路分析
The prompt concerns epoxide opening under acidic conditions and the associated stereochemical outcomes, so let's evaluate each option in turn. Option 1: 'more substituted' — In acid-catalyzed epoxide opening, the nucleophile attacks the more substituted carbon because that carbon bears more positive character after protonation, making it mo......Login to view full explanation

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