题目
题目

CHE 008B A01 SS1 2025 Lecture 3 - Epoxides

多重下拉选择题

Epoxides react with nucleophiles on the less substituted side in basic conditions. This will invert the stereochemistry at the reacting carbon and will not invert the stereochemistry at the non-reacting carbon. This is a SN2 mechanism.

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Topic context: Epoxides opened by nucleophiles under basic conditions follow a backside-type attack that resembles SN2 chemistry, with regioselectivity toward the less hindered carbon and characteristic stereochemical outcomes. Option 1: 'less substituted' — The nucleophil......Login to view full explanation

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