题目
题目

CHE 008B A01 SS1 2025 Lecture 6 - Direction on Substituted Benzenes

多重下拉选择题

Determine whether each statement is TRUE or FALSE.   True All activators are ortho/para directors. False All deactivators are meta directors. True Meta directors do not have a direct interaction between the substitutent and the cation during electrophilic aromatic substitution. True Generally we get ortho and para products together since they have the same interaction with the intermediate cation. False Esters are always ortho/para directors. True Alkyl groups are ortho/para directors. False The identity of the electrophile directs the regioselectivity of electrophilic aromatic substitution True -CF3, -CN, -SO3H, and CHO are all meta directors.

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思路分析
In this exercise, we evaluate eight statements about directing effects in electrophilic aromatic substitution and mark each as True or False. Statement 1: 'True All activators are ortho/para directors.' - Activating substituents generally donate electron density to the ring, stabilizing the arenium ion most effectively at the ortho and para positions. Because of this, activators are indeed typically ortho/para directors. This makes the statement true. Statement 2: 'False All deactivators are meta directors.' - While many deactivating groups are meta directors (e.g., nitro, carbonyl-containing groups), not all deactivators direc......Login to view full explanation

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