What are the DNA complement base pairs for this strand of DNA? 5’ AGTTTA 3’

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Let's break down the problem by recalling base-pairing rules in DNA: Adenine (A) pairs with Thymine (T), and Guanine (G) pairs with Cytosine (C). The given strand is written 5’ to 3’ as AGTTTA. To find the complementary strand, we pair each base with its partner and write the new strand in the opposite 3’ to 5’ orientation relative to the original, which is standard for describing a DNA duplex.

Option a: 3’ CTGGGG 5’. This sequence would imply mismatches like G pairing with C (okay) but the positions do not correspond to the actual A and T in the original strand. For example, after A, we should see T, not C. Similarly, the presence of multiple Gs and the wrong order indicate this is not the correct complement.

Option b: 3’ TCUUUT 5’. The use of U (uracil) signals RNA, not DNA. Since the question concerns DNA base pairing, introducing U makes this option biologically inappropriate for a DNA complement.

Option c: 3’ TCAAAT 5’. This sequence lines up with the correct pairing: A pairs with T, G with C, and the progression from the 5’ end AGTTTA yields a complementary strand reading 3’ TCAAAT 5’. Writing the bases in the 3’ to 5’ direction properly reflects the antiparallel nature of the DNA strands and matches the expected T from pairing with A and C from pairing with G.

In summary, the correct complement must translate each original base to its partner (A↔T, G↔C) and be oriented in the opposite direction (3’ to 5’ if the original is 5’ to 3’). Among the options, only option c adheres to both the correct pairings and the proper orientation, while options a and b either misplace the pairings or introduce a non-DNA residue (U).

ANTH 246 ONL SP25 Week 3 Lecture

What are the DNA complement base pairs for this strand of DNA? 5’ AGTTTA 3’

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