A DNA molecule is composed of two polynucleotides joined by hydrogen bonding between their nitrogenous bases. If the one strand is known to have the nucleotide sequence, ATCCTTCCTA, what must be the complementary strand's nucleotide sequence?

Question

BlackTom AI · Accepted Answer

We start by identifying the base-pairing rules for DNA: adenine (A) pairs with thymine (T), and cytosine (C) pairs with guanine (G). Each nucleotide in the given strand has a complement on the opposite strand.

Take the provided sequence, written 5' to 3' as: A T C C T T C C T A
Determine the complementary bases in order: A pairs with T, so the first complement is T; the second base T pairs with A, giving A; the third base C pairs with G, giving G; the fourth base C pairs with G, giving G; the fifth base T pairs with A, giving A; the sixth base T pairs with A, giving A; the seventh base C pairs with G, giving G; the eighth base C pairs with G, giving G; the ninth base T pairs with A, giving A; the tenth base A pairs with T, giving T.

Putting these complements together in order yields: T A G G A A G G A T, which is written as TAGGAAGGAT.

Note on the question format: there are no provided answer options to evaluate against, so the reasoning above shows the correct complementary sequence derived from base-pairing rules. The key concept to apply is that each nucleotide has a specific, fixed pair on the opposite strand: A↔T and C↔G, read in the corresponding position opposite the given strand.

BIOL 1009 (001-006/050-055) Midterm Exam III

A DNA molecule is composed of two polynucleotides joined by hydrogen bonding between their nitrogenous bases. If the one strand is known to have the nucleotide sequence, ATCCTTCCTA, what must be the complementary strand's nucleotide sequence?

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