The major digestive enzyme secreted by the stomach is___.

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BlackTom AI · Accepted Answer

Question restatement: The major digestive enzyme secreted by the stomach is___.

Option 1: Pepsinogen. This is the correct choice as the stomach primarily secretes pepsinogen, a zymogen released by the chief cells in the gastric glands. In the acidic gastric lumen, pepsinogen is activated to pepsin, which is the active proteolytic enzyme responsible for protein digestion in the stomach.

Option 2: Amylase. Amylase is predominantly produced by the salivary glands and the pancreas, and it digests starch in the mouth and small intestine, not the stomach. Hence, this is not the principal gastric enzyme.

Option 3: Lipase. Lipase acts mainly on fats and is produced mainly by the pancreas (with some gastric lipase from the stomach). While gastric lipase exists, it is not the major digestive enzyme of the stomach as a whole; the primary gastric enzyme focused on is pepsinogen/pepsin for protein digestion.

Option 4: Chymotrypsin. Chymotrypsin is a pancreatic protease released into the small intestine in its active form after activation from trypsinogen; it functions in the small intestine rather than as a primary gastric enzyme.

Putting it together: The stomach’s hallmark digestive enzyme pathway centers on converting pepsinogen to pepsin for protein digestion, making pepsinogen the enzyme class most directly described as the stomach’s major secreted enzyme in this context. The other enzymes listed are associated with salivary glands or the pancreas and operate mainly outside the stomach, or in a different context.

ANSC20002_2025_SM2 Mid Semester exam

The major digestive enzyme secreted by the stomach is___.

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