Which of the following is NOT correct about a competitive inhibitor of an enzyme?

Question

BlackTom AI · Accepted Answer

Question: Which of the following is NOT correct about a competitive inhibitor of an enzyme?

Option 1: 'Its binding to an enzyme is minimised in the presence of large excess of substrate.' This statement is largely accurate for competitive inhibition: when substrate concentration is very high, the substrate outcompetes the inhibitor for the active site, reducing inhibitor binding effectively. So this option describes a correct property of competitive inhibitors.

Option 2: 'It bears a close structural resemblance to the substrate.' This is a classic feature of many competitive inhibitors: they mimic the substrate's geometry to fit into the active site, blocking substrate access. This option is correct.

Option 3: 'It forms an enzyme-inhibitor complex that does not lead to catalysis.' Indeed, the enzyme-inhibitor complex formed at the active site blocks catalysis by preventing substrate turnover. This option correctly describes the mechanism.

Option 4: 'It binds at a site on the enzyme only when the substrate has been bound.' This statement is misleading. Competitive inhibitors typically bind to the active site itself, competing with substrate, and do not require substrate binding to occur; they can bind in the absence of substrate and prevent substrate binding. Hence, this claim misstates the binding behavior and is not correct.

Option 5: 'It binds only at the active site.' This aligns with the classic view of competitive inhibitors: occupancy of the active site by inhibitor prevents substrate binding, and binding occurs at the active site itself. This option is correct.

Summary: Options 1, 2, 3, and 5 describe correct aspects of competitive inhibitors, while option 4 presents an inaccurate statement about the binding requirement. The incorrect statement is option 4. The explanation above walks through each choice, clarifying why the others align with competitive inhibition and why the fourth option does not.

PHR1122 S2 2025 PA D5.2 CYL - Enzyme inhibitors

Which of the following is NOT correct about a competitive inhibitor of an enzyme?

查看解析

登录即可查看完整答案

类似问题

Identify all the correct ways to finish the sentence, A "competitive inhibitor" of an enzyme binds . A. tighter than substrate B. reversibly to the substrate-binding site C. irreversibly to the substrate-binding site

Question at position 11 If something binds to the active site of an enzyme and blocks the substrate from binding, that is an example ofnoncompetitive inhibitioncooperativitycompetitive inhibition

Question16 E = enzyme, S = Substrate, I = Inhibitor Select the term which best describes the type of enzyme inhibition shown in the diagram above. Select one alternative: Allosteric Non-competitive Competitive Irreversible Lineweaver-Burke ResetMaximum marks: 1 Flag question undefined

Which of the following sentences best describes what happens during competitive inhibition of an enzyme?

Students conducting research observe the rate of an enzyme-catalyzed reaction under various conditions with a fixed amount of enzyme in each sample. When will increasing the substrate concentration likely result in the greatest increase in the reaction rate?

In a consumer society, many adults channel creativity into buying things

更多留学生实用工具

考试浏览器助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单