Which biosafety cabinet type is designed to protect both the product and the user from contamination when handling Risk Group 2 microorganisms?

Question

BlackTom AI · Accepted Answer

To address the question, let’s consider what each biosafety cabinet type is designed to protect. 
Option 1: Class I. This cabinet provides protection for the user and the environment but offers no protection for the product. It filters the air entering the cabinet but does not ensure product sterility, which makes it unsuitable when preserving the integrity of the sample itself. 
Option 2: Class III. This is a completely enclosed, gas-tight, negative-pressure cabinet that is used for the highest risk work and typically requires full-body protective gear; it provides maximum product and user protection but is not the standard choice for routine RG2 work since it is more specialized and cumbersome. 
Option 3: Class II. This type balances protection for both the user and the product. It uses HEPA-filtered air for both the inflow and exhaust, maintaining a sterile work area for the sample while protecting the operator. It is specifically designed for handling Risk Group 2 microorganisms where both the product and the user need protection. 
Option 4: Laminar flow hood. A laminar flow hood (often a clean bench) primarily protects the product by delivering HEPA-filtered air across the work surface, but it does not protect the user and can even pose a risk to the operator when handling hazardous materials, making it unsuitable for RG2 containment work. 
In summary, among the choices, Class II cabinets provide dual protection—safeguarding both the product and the user—which matches the requirement for handling RG2 microorganisms. The other options either emphasize protection for the user only, require more specialized use, or protect only the product without user protection.

MIMI2002 (ND) Tute-shop 1 EFT Quiz

Which biosafety cabinet type is designed to protect both the product and the user from contamination when handling Risk Group 2 microorganisms?

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