During bi-phasic cell culture growth in a bioreactor:

Question

BlackTom AI · Accepted Answer

In the context of bi-phasic cell culture growth in a bioreactor, the key idea is that the culture undergoes two distinct growth phases, each often requiring different environmental conditions to optimize cell growth and product formation.

Option provided: 'different growth conditions are provided during early and late stages of growth.' This statement aligns with the fundamental concept of biphasic growth, where the first phase may emphasize promoting cell proliferation (e.g., providing adequate nutrients, optimal pH, temperature, and oxygen transfer), while the second phase may shift toward supporting cell differentiation, product formation, or stress adaptation (which could involve altered feed strategies, oxygen levels, or nutrient ratios). The rationale is that cells have phase-specific needs, and a biphasic approach explicitly acknowledges transitioning conditions to match those needs.

Consider why this makes sense: during early growth, cells prioritize biomass accumulation, which benefits from conditions that maximize division rates and viability. In the late phase, metabolic shifts occur, and conditions are often tuned to favor product synthesis, secretion, or maintenance of cell health under accumulated metabolic byproducts. Adopting different conditions at these stages can prevent nutrient depletion, limit inhibitory byproducts, and optimize overall culture performance.

If there were other options, one would expect them to claim that single, unchanging conditions suffice throughout the culture, or that all phases require identical parameters regardless of biological state. Such statements would conflict with the well-established practice of fed-batch and biphasic strategies, where dynamic adjustment of parameters is common. In this case, since no alternative options are provided to contrast, the single statement stands as the reflection of biphasic culture design.

In summary, recognizing that early and late growth stages demand distinct environmental settings embodies the core logic of biphasic culture strategies, supporting better control over growth kinetics and product outcomes.

BIOT5750.39480.202530 Module 5 Quiz S25

During bi-phasic cell culture growth in a bioreactor:

查看解析

登录即可查看完整答案

类似问题

In a consumer society, many adults channel creativity into buying things

Economic stress and unpredictable times have resulted in a booming industry for self-help products

People born without creativity never can develop it

A product has a selling price of $20, a contribution margin ratio of 40% and fixed cost of $120,000. To make a profit of $30,000. The number of units that must be sold is: Type the number without $ and a comma. Eg: 20000

Which of the following statement regarding cost is correct:

Under the assumptions used in cost-volume-profit analysis, as the activity increases:

The CVP and break-even analysis are supported by a range of important assumptions. Which of the following is not an assumption of the CVP:

The break-even point is that at which:

更多留学生实用工具

考试浏览器助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单