What role does autophagy play in cellular homeostasis?

Question

BlackTom AI · Accepted Answer

The question asks about the role of autophagy in cellular homeostasis. Autophagy is a cellular degradation and recycling process that helps maintain homeostasis by clearing out damaged or dysfunctional organelles, misfolded or aggregated proteins, and other cellular debris. Through autophagy, cells break down these components in lysosomes, reclaiming nutrients and building blocks that can be reused for energy production and biosynthesis, which supports energy balance and metabolic flexibility.

In this context, the stated answer, 'Cellular cleaning and recycling,' captures the core function of autophagy: cleaning up cellular components (quality control) and recycling their constituent molecules (nutrient reclamation). This aligns with established concepts in cell biology, where autophagy contributes to organelle turnover (e.g., mitophagy for mitochondria), proteostasis, and adaptation to stress by maintaining cellular quality and supplying substrates during nutrient scarcity.

Because the provided data does not include any alternative answer options, there is no basis here to evaluate multiple choices or identify incorrect statements. If other options were present, they would be assessed for accuracy relative to the primary roles of autophagy described above, such as nutrient recycling, removal of damaged organelles, and participation in cellular stress responses. Nevertheless, the described role of autophagy as 'cellular cleaning and recycling' accurately reflects its fundamental contribution to cellular homeostasis.

2261 BIOSC 1500 SEC1030 Cell Bio 1500'25 first midterm, 75 min version

What role does autophagy play in cellular homeostasis?

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