Autophagosomes contain components of the cell that are breaking down (eg. damaged ER, worn-out mitochondria) and have become sequestered in the cell by a membrane.

Question

BlackTom AI · Accepted Answer

Begin by restating what the question is asking: whether autophagosomes contain cellular components that are undergoing breakdown and have been sequestered by a membrane.
Option 1: True. This aligns with the core concept of autophagy in which damaged organelles or cytoplasmic constituents are enclosed by an isolation membrane to form an autophagosome, which then fuses with a lysosome for degradation. The description mentions damaged ER and worn-out mitochondria, which are classic substrates targeted by selective autophagy, consistent with known cellular pathways.
Option 2: False. This would be incorrect because it contradicts established biology: autophagosomes are defined as double-mymembrane vesicles that sequester cytoplasmic material for degradation, not as empty or non-sequestered structures. Claiming that autophagosomes do not contain breakdown-ready components overlooks the fundamental purpose of autophagy and the composition of autophagosomes.
To further dissect, consider what autophagosomes are: a membrane-bound vesicular compartment that engulfs portions of cytoplasm, organelles, or protein aggregates marked for turnover. The engulfed material is precisely what is degraded after fusion with lysosomes, reinforcing why the statement describes autophagosomes accurately.
In contrast, if one reads the statement as implying autophagosomes are not involved with sequestration or degradation, it would misrepresent the essential mechanism of autophagy, making the falsity of that option clear. Overall, the correct framing is that autophagosomes do contain components slated for breakdown and are formed by membrane sequestration.

AVBS2005 (ND) Cytology II

Autophagosomes contain components of the cell that are breaking down (eg. damaged ER, worn-out mitochondria) and have become sequestered in the cell by a membrane.

查看解析

登录即可查看完整答案

类似问题

What role does autophagy play in cellular homeostasis?

Autophagy activated under nutrient-rich conditions

Lysosomes fuse with autophagosomes to form autolysosomes

The process of autophagy depends on ATP

Autophagy is primarily a destructive process with no role in cell survival.

You discover a new compound that adversely affects the functioning of lysosomes. What might be the consequence of this compound when it is applied to cells?

DNA autophagy contributes to cell rejuvenation at the cellular level.

Which coenzyme is the most important for autophagy?

更多留学生实用工具

考试浏览器助手

风格化写作助手

论文查重助手

文献引用助手

课堂转译助手

课堂笔记助手

Quiz搜索助手

学校历年真题

智能刷题助手

智能匹配练习

希望你的学习变得更简单