Observe the data shown below. What is being shown?

Question

BlackTom AI · Accepted Answer

The task asks us to identify what type of data is being shown in the figure.
Option a. ATAC-seq: This method produces chromatin accessibility profiles with narrow, sharp peaks across the genome, often aligned to gene loci and annotated with nearby genes (as seen with UCSC Genes). The plot displays multiple tall peaks at a locus with labeled coordinates (e.g., 212, 221) and a schematic gene track beneath, which is characteristic of ATAC-seq visualizations used to highlight accessible regulatory regions.
Option b. scRNA-seq: Single-cell RNA sequencing data are typically shown as heatmaps, violin plots, or t-SNE/UMAP embeddings illustrating gene expression across cells, rather than a genomic track with chromatin features. The image lacks cell-by-cell expression plots and is not a transcriptomic matrix representation.
Option c. Linkage analysis: This type of analysis is used in genetics to map disease genes by recombination patterns, and its results are usually shown as LOD score plots, pedigrees, or haplotype maps, not intuitive chromatin accessibility peaks with a gene track.
Option d. RNA-seq: RNA sequencing data are represented as read density across transcripts or genome, but classic RNA-seq visualization emphasizes expression levels rather than discrete chromatin accessibility peaks at regulatory elements. While RNA-seq can have coverage tracks, the depicted sharp peaks with an explicit gene annotation track match ATAC-seq styling more closely.
Overall, the presence of distinct, sharp peaks indicating accessible regions along the genome, coupled with a gene annotation track, aligns best with ATAC-seq data visualization rather than the other options.

DEV3011 S1 2025 Week 12 Self Quiz

Observe the data shown below. What is being shown?

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