题目
题目

BIOL3611.13541.202610 LA4SP2025

单项选择题

Assume a mutation in the CCA arm of tRNAThr occurs that reduces the flexibility of this region of the molecule but still allows the 3′ end of the tRNA to enter the aminoacyl-tRNA synthetase activation site. Which of the following is the most likely outcome?

选项
A.The tRNAThr may become charged with Ser but will not undergo proofreading.
B.The tRNAThr will never be attached to Ser.
C.he tRNAThr will never be attached to Thr.
D.The tRNAThr may become charged with Ser but will undergo proofreading to remove the Ser.
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标准答案
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思路分析
Consider the scenario: a mutation in the CCA arm of tRNAThr reduces flexibility but still permits the 3′ end to enter the aminoacyl-tRNA synthetase activation site. This setup specifically tests whether misacylation can occur and whether the proofreading/editing function can correct it. Option 1: 'The tRNAThr may become charged with Ser but will not undergo proofreading.' This option suggests that Ser could be attached and that no proofreading/editing would occur. In many aminoacy......Login to view full explanation

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