Vitamin D can be made in the body with the help of

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Question restatement: Vitamin D can be made in the body with the help of
Options: [bacteria., tryptophan., vitamin A., sunlight., exercise.]

Option 1: bacteria. This is incorrect because vitamin D synthesis occurs in human skin via exposure to ultraviolet B (UVB) radiation, not by bacteria. Bacteria can synthesize many vitamins, but not the human vitamin D pathway in this context.

Option 2: tryptophan. Tryptophan is an essential amino acid involved in protein synthesis and as a precursor to serotonin and melatonin, not to vitamin D synthesis. The body does not convert tryptophan into vitamin D.

Option 3: vitamin A. Vitamin A is a fat-soluble vitamin important for vision and immunity, but it has no role in enabling the skin to produce vitamin D. The production of vitamin D relies on cholesterol in the skin and UVB exposure, not on vitamin A.

Option 4: sunlight. Sunlight, specifically UVB radiation from the sun, activates the synthesis of vitamin D in the skin by converting 7-dehydrocholesterol to previtamin D3, which is then processed to active vitamin D. This is the correct mechanism for endogenous vitamin D production.

Option 5: exercise. Physical activity has numerous health benefits but does not directly enable the biochemical synthesis of vitamin D in the body. Synthesis requires UVB exposure and substrate (7-dehydrocholesterol) in the skin.

Summary of reasoning: The vitamin D synthesis pathway in humans is initiated by UVB light from sunlight acting on skin cholesterol (7-dehydrocholesterol), leading to the production of previtamin D3 and ultimately active vitamin D. The other options do not participate in this biochemical process and are not involved in enabling vitamin D production.

HUMNNTR 2200 SP2025 (15810) Learning Module: Bone Health

Vitamin D can be made in the body with the help of

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