Question at position 28 The first vaccine developed was against ________.CowpoxChicken choleraRabiesSmallpoxClear my selection

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The question asks about the first vaccine developed. We'll evaluate each option in turn.
Option 1: Cowpox. This is the correct historical answer, because the smallpox vaccine was developed by Edward Jenner in 1796 using material from cowpox infection to confer immunity to smallpox. Jenner observed that milkmaids who had contracted cowpox appeared immune to smallpox, and he demonstrated that inoculation with cowpox protected against smallpox, establishing the first vaccine concept.
Option 2: Chicken cholera. This disease became notable later in vaccine history due to Louis Pasteur's work on fowl cholera, where a weakened culture provided protection. However, chicken cholera is not the first vaccine; it represents an important early vaccine study but not the earliest.
Option 3: Rabies. The rabies vaccine was developed by Louis Pasteur and Émile Roux in the 19th century, after the era of Jenner, and represents a significant milestone in rabies prevention but not the first vaccine overall.
Option 4: Smallpox. While the target of Jenner’s vaccine was smallpox, the vaccine was derived from cowpox material, not directly from smallpox itself. The sequence matters: the vaccine used cowpox to confer immunity to smallpox, so smallpox is not the substance used to create the first vaccine.
In summary, among the options, cowpox stands out as the foundational material used to inoculate against smallpox and thus marks the first vaccine in medical history.

Question at position 28 The first vaccine developed was against ________.CowpoxChicken choleraRabiesSmallpoxClear my selection

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