Which effect is least commonly due to transposons?

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Question restatement: Which effect is least commonly due to transposons? Options: gene disruption, increased DNAse sensitivity, increased possibility of homologous recombination, altered gene regulation.
Option 1: gene disruption. Transposons insert into genomes and can interrupt coding sequences or regulatory regions, frequently causing gene disruption. This is a well-documented and common consequence of transposon activity.
Option 2: increased DNAse sensitivity. DNAse sensitivity reflects chromatin accessibility. While transposon insertions can influence chromatin structure, making nearby regions more or less accessible, this is not the most straightforward or common direct consequence attributed to transposons, and is less consistently observed as an outcome compared to disruption or regulatory effects. This makes it a less typical or frequent consequence.
Option 3: increased possibility of homologous recombination. Transposable elements can provide homologous sequences that promote ectopic or unequal recombination between non-allelic sites, increasing recombination events. This is a recognized indirect consequence of repetitive elements like transposons.
Option 4: altered gene regulation. Transposon insertions often bring promoter or enhancer elements, silencers, or insulators that can modulate the expression of nearby genes, a common outcome of transposon activity.
Summary: The most consistently observed and documented effects of transposons are gene disruption, altered regulation, and increased recombination potential. While transposons can influence chromatin accessibility, the direct, routinely described outcome of increased DNAse sensitivity is less characteristic than the others, making it the least commonly attributed effect among the options.

BIOL_2004_81774_202509 Homework 2

Which effect is least commonly due to transposons?

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