Question at position 3 In eukaryotes, RNA polymerase binds to a _____________ called the ____________ region.sequence of DNA;transcriptsequence of DNA; promoterprotein; promoterNone of the above, eukaryotes do not use RNA polymeraseprotein: transcriptClear my selection

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Question at position 3 In eukaryotes, RNA polymerase binds to a _____________ called the ____________ region.sequence of DNA;transcriptsequence of DNA; promoterprotein; promoterNone of the above, eukaryotes do not use RNA polymeraseprotein: transcriptClear my selection

BlackTom AI · Accepted Answer

The question asks about where RNA polymerase binds in eukaryotes and what region is involved in that binding. 
Option 1: 'sequence of DNA; transcript' This pairing suggests binding to a transcript, which is RNA, but RNA polymerase binds to DNA to initiate transcription, not to the RNA product itself. So this is not accurate for the binding site described.
Option 2: 'sequence of DNA; promoter' This reflects the canonical view: RNA polymerase recognizes and binds to a specific DNA sequence located upstream of a gene, called the promoter region, to begin transcription. The promoter is the DNA region that guides the initiation machinery.
Option 3: 'protein; promoter' Here, the statement misattributes the binding site to a protein rather than the DNA sequence. While various transcription factors are proteins that interact with promoters, the initial binding of RNA polymerase itself is to the DNA promoter region, not directly to a protein in this context. Therefore this option misframes the primary binding substrate.
Option 4: 'None of the above, eukaryotes do not use RNA polymerase' This is factually incorrect because eukaryotic cells rely on RNA polymerases (I, II, III) for transcription; the statement denies a fundamental aspect of molecular biology.
Option 5: 'protein: transcript' This option pairs 'protein' with 'transcript,' which does not reflect the promoter-based initiation binding of RNA polymerase to DNA, so it is inaccurate with respect to the described mechanism.
In summary, the core concept is that RNA polymerase binds to a DNA sequence that constitutes the promoter region to initiate transcription, rather than binding to a transcript or to a protein, and not denying the role of RNA polymerase in eukaryotic transcription. The option that aligns with this mechanism is the one describing a 'sequence of DNA' and the 'promoter' region.

Question at position 3 In eukaryotes, RNA polymerase binds to a _ called the region.sequence of DNA;transcriptsequence of DNA; promoterprotein; promoterNone of the above, eukaryotes do not use RNA polymeraseprotein: transcriptClear my selection

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