iPS cells have been used successfully to accomplish all of the following in vitro EXCEPT:

Question

BlackTom AI · Accepted Answer

This question asks which item is NOT something iPS cells have been used for in vitro. To approach this, I’ll evaluate each option on its own merits.
Option: 'Produce human neurons' – Induced pluripotent stem (iPS) cells can be guided to differentiate into neural lineages and produce human neurons in vitro. This is a well-established application and a core use of iPS technology in neuroscience research and disease modeling.
Option: 'None of the other answers' – If every other listed use is something iPS cells have indeed achieved in vitro, then the statement that none of the other answers are true would be accurate, making this the selection that corresponds to the exception in a question framed as 'EXCEPT.'
Option: 'Study human disease mechanisms' – iPS cells are widely used to model human diseases by deriving patient-specific cells and studying disease pathways, mechanisms, and phenotypes in a dish. This is a common and well-supported application.
Option: 'Engineer developing cells into tissue-like structures' – iPS-derived cells are used in organoid and tissue engineering approaches to create tissue-like structures and organoids, enabling more complex in vitro studies.
Option: 'Test toxicity of drugs in human cells' – iPS-derived cells are routinely used for in vitro toxicity testing to assess drug safety in human cell types, including hepatocytes and neurons.

Taken together, each of the first, third, fourth, and fifth options reflects established iPS cell applications in vitro. The 'None of the other answers' option is therefore the statement that fits the EXCEPT item, since all the other options describe true uses of iPS cells in vitro. The reasoning shows that there isn’t an option among the others that is NOT an iPS application, making 'None of the other answers' the correct choice in the EXCEPT sense.

01:146:447:01 CLINICAL NEUROBIO CN F25 Exam 1

iPS cells have been used successfully to accomplish all of the following in vitro EXCEPT:

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