Which of the following normally leads to the production of functional messenger RNA in eukaryotic cells?

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BlackTom AI · Accepted Answer

In eukaryotic cells, the production of functional messenger RNA (mRNA) involves not just transcription but also RNA processing steps that convert the primary transcript into a mature, translatable mRNA. 
Option 1: 'The removal of portions of RNA known as intervening sequences (introns)' corresponds to RNA splicing, a key processing step that yields functional mRNA by removing non-coding introns and joining exons. This is a central feature of eukaryotic mRNA maturation. 
Option 2: 'A decrease in the rate of ribosome synthesis' relates to ribosome production, not to mRNA synthesis or processing. It does not directly produce functional mRNA. 
Option 3: 'The formation of peptide bonds between adjacent nucleotides' misstates molecular biology: peptide bond formation occurs during translation between amino acids, not during mRNA generation. mRNA production is a nucleic-acid synthesis process, not a peptide synthesis one. 
Option 4: 'A decrease in RNA polymerase activity' would generally lower or impede transcription, reducing mRNA synthesis rather than producing functional mRNA. While connected, this describes a reduction rather than a processing event that yields functional mRNA. 
Option 5: 'The replication of new messenger RNA molecules from existing messenger RNA molecules' is incorrect because mRNA is not replicated from existing mRNA; new mRNA is synthesized from a DNA template through transcription, and mature mRNA is formed via processing, not by copying from another mRNA strand. 
Taken together, the correct mechanism that normally leads to production of functional mRNA in eukaryotes is the removal of introns during RNA processing, i.e., splicing.

APBIO142-030 with labs S17 - CollegeBoard* AP Exam Prep: Multiple Choice

Which of the following normally leads to the production of functional messenger RNA in eukaryotic cells?

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