A bacterium entering the body through a small cut in the skin will do which of the following?

Question

A bacterium entering the body through a small cut in the skin will do which of the following?

BlackTom AI · Accepted Answer

When a bacterium enters via a skin cut, the body mounts an immediate innate immune response, and several options require evaluation for plausibility.

Option a: 'Stimulate release of interferons.' Interferons are cytokines primarily associated with antiviral defenses and signaling to neighboring cells to establish an antiviral state. While bacteria can induce some cytokine release, interferons are not the principal or most direct response to extracellular bacterial invasion. This makes this choice less accurate as the main immediate effect.

Option b: 'Stimulate Natural Killer cell activity.' Natural Killer (NK) cells are part of the innate immune system and are especially important for identifying and killing virus-infected or stressed cells. They are less engaged by ordinary extracellular bacterial infections occurring through a skin breach, making this option not the best description of the typical first-line response.

Option c: 'Stimulate apoptosis of nearby body cells.' Inducing apoptosis of neighboring healthy cells is not a standard or intended outcome of a simple bacterial entry through a wound. Apoptosis is a controlled cell death process used in development or to remove severely damaged cells, but is not a primary defense mechanism activated by a superficial bacterial entry.

Option d: 'Inactivate the erythrocytes.' Erythrocytes (red blood cells) are not the target of immediate antibacterial defenses in this context. Inactivating them would be harmful and is not a recognized immune mechanism against bacteria at a wound site.

Option e: 'Activates a group of proteins called complement.' The complement system is a key part of innate immunity activated in response to bacteria. It helps opsonize pathogens, attract immune cells, and form membrane attack complexes to lyse bacteria. This is the most accurate and directly relevant mechanism for a bacterium entering through a skin cut.

In summary, among the given options, activating complement (option e) aligns with the typical immediate immune response to extracellular bacteria entering through a wound, whereas the other options describe responses that are either antivirally specific or not characteristic of a primary bacterial wound response.

IMM3802 - MUM S2 2025 Semester test

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