Production of truncated proteins is commonly caused by which type of mutation?

Question

BlackTom AI · Accepted Answer

Question restatement: Production of truncated proteins is commonly caused by which type of mutation?

Option 1: Expanding trinucleotide repeats. While expanded repeats can cause disease through toxic RNA or protein products and sometimes frameshifts or altered protein function, they are not the classic mechanism producing truncated proteins via premature stop codons. This answer is not the standard explanation for truncation.

Option 2: Suppressor. Suppressor mutations can sometimes mitigate the effects of a primary mutation (e.g., by suppressing a stop codon in certain contexts), but they do not inherently cause truncated proteins. In isolation, this option does not describe the usual cause of truncation.

Option 3: Missense. Missense mutations change a single amino acid but typically do not introduce a premature stop codon; thus they do not inherently produce truncated proteins. This option explains another type of alteration, not truncation.

Option 4: Gain-of-function. Gain-of-function mutations introduce new or enhanced activities, not truncation of the protein. They can alter function but are not the primary mechanism for truncation.

Option 5: Nonsense. Nonsense mutations create premature stop codons, leading to early termination of translation and production of truncated proteins. This is the classic and direct mechanism by which truncated proteins arise.

To summarize, the key concept is that a nonsense mutation introduces a stop signal in the coding sequence, resulting in shortened, truncated proteins, whereas the other options involve different types of sequence changes that do not inherently produce truncation.

BIOL_2004_81774_202509 Genetics Test 4- Requires Respondus LockDown Browser

Production of truncated proteins is commonly caused by which type of mutation?

View Explanation

Log in for full answers

Similar Questions

What type of point mutation leads to the introduction of a stop codon in mRNA sequence?

A _________ mutation changes a codon that specifies an amino acid into one that terminates translation.

What type of point mutation leads to the introduction of a stop codon in mRNA sequence?

What is the result of a nonsense mutation in a coding sequence?

In a consumer society, many adults channel creativity into buying things

Economic stress and unpredictable times have resulted in a booming industry for self-help products

People born without creativity never can develop it

More Practical Tools for Students Powered by AI Study Helper

Homework AI Solver

Stylized AI Paper Writer

Plagiarism Checker Assistant

Citation AI Academic Writing Tool

In-Class Translation Assistant

AI Note Generator

AI Quiz Answers

Past Exam Questions from University Test Bank

Smart Practice Assistant

Adaptive Practice

Making Your Study Simpler