Which go together?

Question

Which go together?

BlackTom AI · Accepted Answer

The question asks which items go together in the context of receptor types.
Here, the given phrase is 'ionotropic, GABA-A, ligand-gated channel.'
First, consider what 'ionotropic' means: ionotropic receptors are those that form an ion channel and open in response to ligand binding, enabling direct ion flow across the membrane.
Next, 'GABA-A' refers to a specific receptor subtype for GABA that is known to be ionotropic and acts as a ligand-gated chloride channel, allowing Cl- ions to pass when activated by GABA or pharmacological ligands.
Finally, 'ligand-gated channel' is the characteristic functional description of ionotropic receptors, including GABA-A receptors; binding of a ligand directly opens an ion channel.
Putting these pieces together, the components ionotropic, GABA-A, and ligand-gated channel all describe the same receptor class: a receptor type that is activated by ligand binding and forms an ion channel, with GABA-A as a canonical example.
In contrast, if one were to mix with metabotropic receptors (which are G-protein-coupled and do not form ion channels) or with non-ion channel modalities, the pair would no longer align with the ionotropic, ligand-gated channel concept.
Thus, the trio provided—ionotropic, GABA-A, ligand-gated channel—fits coherently as a group describing this receptor category.

PSYC181_WI25_A00 EXAM 2

Which go together?

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