Ion channels located on the plasma membrane of a muscle, which open in response to binding of acetylcholine, are an example of a:

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Question restatement: The scenario describes ion channels on the muscle cell plasma membrane that open when acetylcholine binds to them, which is a ligand-based trigger.
Option 1: 'sodium-potassium pump' — This is a transporter that uses active transport to move Na+ and K+ across the membrane, not a channel that opens in response to a chemical signal. It does not fit the description of a channel gated by ligand binding. This choice mislabels an enzyme/transporter as a gated channel.
Option 2: 'mechanically-gated ion channel' — These channels respond to mechanical deformation (such as stretch or pressure) of the membrane, not to chemical binding. Since the stimulus is chemical (acetylcholine), this option does not match.
Option 3: 'voltage-gated ion channel' — Voltage-gated channels open in response to changes in membrane potential (voltage), not to ligand binding. The trigger described is chemical, so this option is incorrect.
Option 4: 'ligand-gated ion channel' — This type of channel opens when a ligand, such as acetylcholine, binds to its receptor, allowing ion flow across the membrane. This directly aligns with the given scenario and is the correct mechanism described.
Option 5: 'leak channel' — Leak channels are typically always open and are not gated by ligand binding or voltage or mechanical stimuli. They do not respond specifically to acetylcholine binding, so this choice does not fit the description.
In summary, each incorrect option either describes a transporter (not a channel), or a gate mechanism that relies on mechanical, voltage, or constitutive openness rather than ligand binding. The correct mechanism is the ligand-gated ion channel, which opens upon acetylcholine binding to its receptor on the muscle cell membrane.

9808 WINTER 2025 BRUCE INTENSIVE Laboratory Exam 1: Undergraduate Students (9808)

Ion channels located on the plasma membrane of a muscle, which open in response to binding of acetylcholine, are an example of a:

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