The flat bones of the skull are formed directly within mesenchyme. What is this type of bone development known as?

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BlackTom AI · Accepted Answer

The question asks about the type of bone development in which flat bones of the skull form directly within mesenchyme.
Option 1: Osteoclast deposition. This describes a resorptive process carried out by osteoclasts, not a mode of bone formation from mesenchyme, so it does not answer the question.
Option 2: Endochondral ossification. This pathway involves bone developing from a cartilage mold, which is typical for long bones but not for the flat bones of the skull, making it incorrect in this context.
Option 3: Appositional Growth. While this process increases the diameter and thickness of existing bones by adding new bone to the outer surface, it does not describe the initial formation of flat skull bones from mesenchyme, so it’s not the right choice here.
Option 4: Intramembranous ossification. This is the process where mesenchymal cells differentiate directly into osteoblasts, forming osteoid that mineralizes to become bone, which is precisely how the flat bones of the skull develop. Therefore, this option correctly identifies the development mode.

ANAT20006_2025_SM1 Practice Questions: Mid-Semester Test #1

The flat bones of the skull are formed directly within mesenchyme. What is this type of bone development known as?

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