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CHE 008B A01 SS1 2025 Lecture 7 - Organometallic Reagents
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An organometallic reagent with a ketone makes a tertiary alcohol . Formaldehyde with an organometallic makes a primary alcohol . An aldehyde with an organometallic reagent makes a secondary alcohol
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Here’s the logic behind how organometallic reagents react with different carbonyl compounds to give alcohols after workup.
First, consider a ketone reacting with an organometallic reagent (such as a Grignard or organolithium): the organometallic adds its alkyl (or aryl) group to the carbonyl carbon, gener......Login to view full explanationLog in for full answers
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