Question at position 1 The human genome was first sequenced in 2003 and cost approximately $3 billion. Why can we easily sequence ourselves or even our dogs today?The government now subsidizes genetic testing for everyoneIncreased willingness to share genetic dataIncreased funding for dog genetics researchMajor advancements in sequencing technology made it significantly cheaperClear my selection

Question

Question at position 1 The human genome was first sequenced in 2003 and cost approximately $3 billion. Why can we easily sequence ourselves or even our dogs today?The government now subsidizes genetic testing for everyoneIncreased willingness to share genetic dataIncreased funding for dog genetics researchMajor advancements in sequencing technology made it significantly cheaperClear my selection

BlackTom AI · Accepted Answer

Here we have a question about why sequencing humans or dogs today is much cheaper than the initial human genome project.
Option 1: 'The government now subsidizes genetic testing for everyone' This is not accurate as a universal subsidy policy for genetic testing does not exist in most countries, and subsidies would not by themselves dramatically drop sequencing costs across the board.
Option 2: 'Increased willingness to share genetic data' While greater data sharing helps research and collaboration, it does not directly reduce the actual cost of sequencing per sample; it affects data access and use rather than the sequencing chemistry or hardware costs.
Option 3: 'Increased funding for dog genetics research' Funding for dog genetics research could accelerate specific projects, but it does not explain the broad decline in sequencing costs for all organisms, including humans and dogs, across the board.
Option 4: 'Major advancements in sequencing technology made it significantly cheaper' This is the core reason: improvements in sequencing technologies (like next-generation sequencing, improved chemistry, higher throughput, parallelization, and reduced per-base costs) dramatically lowered the cost per genome, enabling cost reductions from billions to a few thousand dollars in a few years. It directly explains the widespread affordability.
Overall, the options that focus on subsidies, data-sharing, or targeted funding do not inherently account for the universal drop in sequencing costs, whereas technological advancements that reduce per-base costs provide the correct mechanistic explanation for why sequencing became so affordable.

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