Prolonged exposure to an agonist leading to a diminished response despite continued presence of the drug is known as:

Question

BlackTom AI · Accepted Answer

Question restatement: Prolonged exposure to an agonist leading to a diminished response despite continued presence of the drug is known as:

Option 1 - Bioavailability: Bioavailability refers to the fraction of an administered dose that reaches systemic circulation and is available to have an effect. It is about the amount of drug that enters the bloodstream, not about the body’s changing response over time with continued exposure. This option does not describe a decreased response due to ongoing drug presence.

Option 2 - Tolerance: Tolerance describes a pharmacodynamic or pharmacokinetic phenomenon where a person’s response to a drug diminishes with repeated use, requiring higher doses to achieve the same effect, even though the drug is still present. This directly matches the scenario of diminishing response despite continued exposure.

Option 3 - Potentiation: Potentiation occurs when one drug increases the effect of another drug, enhancing potency beyond what would be expected from either drug alone. This is about interaction that elevates effects, not a reduced response due to continued exposure.

Option 4 - Synergism: Synergism refers to two or more drugs producing an effect greater than the sum of their individual effects. Like potentiation, this describes an enhanced combined action, not a decreased response from prolonged exposure to a single drug.

In summary, among the choices, the phenomenon that best fits the description of a diminished response after ongoing exposure to the agonist is tolerance, while the other terms describe different pharmacokinetic or pharmacodynamic relationships.

PCOL2021 (ND) Module 1 Quiz

Prolonged exposure to an agonist leading to a diminished response despite continued presence of the drug is known as:

View Explanation

Log in for full answers

Similar Questions

Tolerance refers to needing less of a substance over time to achieve the same effect.

With repeated administration of cocaine:

Tolerance:

Overtime the body start to develop a _________________________ for opioids.

In a consumer society, many adults channel creativity into buying things

Economic stress and unpredictable times have resulted in a booming industry for self-help products

People born without creativity never can develop it

A product has a selling price of $20, a contribution margin ratio of 40% and fixed cost of $120,000. To make a profit of $30,000. The number of units that must be sold is: Type the number without $ and a comma. Eg: 20000

More Practical Tools for Students Powered by AI Study Helper

Homework AI Solver

Stylized AI Paper Writer

Plagiarism Checker Assistant

Citation AI Academic Writing Tool

In-Class Translation Assistant

AI Note Generator

AI Quiz Answers

Past Exam Questions from University Test Bank

Smart Practice Assistant

Adaptive Practice

Making Your Study Simpler