Questions
W25 BIOL D006B 01Y Cell & Molecular Biology Lecture Exam 1
Single choice
Which of the following statements correctly describes the difference between the leading strand and the lagging strand in DNA replication?
Options
A.The leading strand is synthesized continuously in the 5'→ 3' direction, while the lagging strand is synthesized discontinuously in the 5'→ 3' direction.
B.The lagging strand requires an RNA primer, whereas the leading strand does not.
C.The leading strand is synthesized by adding nucleotides to the 3' end of the growing strand, and the lagging strand is synthesized by adding nucleotides to the 5' end.
D.The leading strand is synthesized in the 3'→ 5' direction in a discontinuous fashion, while the lagging strand is synthesized in the 5'→ 3' direction in a continuous fashion.
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Step-by-Step Analysis
Question restatement: Which of the following statements correctly describes the difference between the leading strand and the lagging strand in DNA replication?
Option 1: The leading strand is synthesized continuously in the 5'→ 3' direction, while the lagging strand is synthesized discontinuously in the 5'→ 3' direction. This is a true description of the core difference: DNA polymerase adds nucleotides in the 5' to 3' direction, and the leading strand is synthesized as a continuous polymer as the fork opens, whereas t......Login to view full explanationLog in for full answers
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Dr. Dre has decided that he wants to cure cancer and so has designed a bunch of compounds to inhibit various enzymes involved in DNA replication. He tests each of the 5 compounds against the enzymatic activity of each of the DNA replication enzymes and records what each one does to work out what they do. He concludes that [ Select ] Compound B Compound E Compound D Compound A Compound C would prevent the replacement of RNA sequences with DNA, while [ Select ] Compound B Compound C Compound D Compound A Compound E would prevent all steps in DNA replication. He predicts that [ Select ] Compound E Compound D Compound B Compound C Compound A would leave the replicated DNA strand as a series of separate DNA fragments, but that [ Select ] Compound A Compound B Compound D Compound E Compound C would lead to the death of the cell upon DNA replication. Finally, he concludes that [ Select ] Compound D Compound C Compound A Compound E Compound B would prevent the formation of both the leading and lagging strands.
Dr. Dre has decided that he wants to cure cancer and so has designed a bunch of compounds to inhibit various enzymes involved in DNA replication. He tests each of the 5 compounds against the enzymatic activity of each of the DNA replication enzymes and records what each one does to work out what they do. He concludes that [ Select ] Compound A Compound D Compound E Compound B Compound C would prevent the replacement of RNA sequences with DNA, while [ Select ] Compound C Compound B Compound E Compound A Compound D would prevent all steps in DNA replication. He predicts that [ Select ] Compound A Compound E Compound B Compound C Compound D would leave the replicated DNA strand as a series of separate DNA fragments, but that [ Select ] Compound C Compound D Compound B Compound E Compound A would lead to the death of the cell upon DNA replication. Finally, he concludes that [ Select ] Compound B Compound C Compound A Compound E Compound D would prevent the formation of both the leading and lagging strands.
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